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Yes, seis is in the scrabble dictionary

...and is worth 4 points by itself.

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seis

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Here are some other words you could make with the letters seis, you can also
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Top Words by points

Points

Word Game

seis

4

Scrabble

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2 Letters

Scrabble® Points

es

2

is

2

si

2

3 Letters

Scrabble® Points

ess

3

sei

3

sis

3

4 Letters

Scrabble® Points

seis

4

Found 7 words in 0.12881 seconds